Jesus taught them that those who were opposed to God would hate them, too.

John 15:18—16:4

18 “The people who are opposed to God will hate you. When that happens, remember that they hated me first. 19 If you belonged to those who are opposed to God [MTY], they would love you like they love those who belong to them. But you do not belong to those who are opposed to God [MTY]. Instead, I chose you so that you would separate yourselves from [MTY] them. That is why those who are opposed to God [MTY] hate you. 20 Remember these words that I told you: ‘No servant is greater than his master.’ That means that you, who are like my servants, cannot expect people to treat you better than they treat me. So, since they have ◄persecuted me/caused me to suffer►, they will ◄persecute you/cause you to suffer► also. If they had paid attention to the things I taught them, they would pay attention to what you teach them. 21 They will treat you like that because you belong to me [MTY], and because they do not know the one who sent me. 22 If I had not come and spoken God’s message to them, they would not be guilty of rejecting me and my message. But now I have come and told them God’s message, so they will have no excuse when God judges them for their sin. 23 All those who hate me, it is as though they hate my Father as well. 24 If I had not done among them the miracles that no one else ever did, they would not be guilty of the sin of rejecting me. But now, although they have seen those miracles, they have hated both me and my Father. 25 But this has happened in order that these words that have been written in their Scriptures might be fulfilled {to fulfill this that ◄someone/the Psalmist► wrote in their Scriptures}: ‘They hated me for no reason.’

26 Later I will send to you from my Father the one who will ◄encourage/be like a legal counsel for► you. He is the Spirit who will teach you God’s truth. He will come from my Father. He will tell people about me. 27 But you disciples must also tell people about me, because you have been with me from the time when I started my ministry [MTY].”

16 Jesus continued by saying to us, “I have told you these things in order that you will not stop trusting in me when people ◄cause you to suffer/persecute you►. 2 They will not allow you to worship in ◄synagogues/their meeting places►. In fact, there will be a time when anyone who kills you will think that he is serving God by doing that. 3 They will do such things because they have never known who I really am, nor who my Father is. 4 I have told you these things in order that when they start ◄to cause you to suffer/to persecute you► [MTY], you will remember that I warned you. I did not tell you these things when you first started to accompany me [MTY] because I was with you, and they were causing trouble for me, not for you.”